| Autor: |
Risslegger, B., Lass-Flörl, C., Blum, G., Lackner, M. |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; April 2015, Vol. 59 Issue: 6 p3675-3682, 8p |
| Abstrakt: |
ABSTRACTFor antifungal susceptibility testing of nonsporulating or poorly sporulating dermatophytes, a fragmented-mycelium inoculum preparation method was established and compared to broth microdilution testing according to CLSI and EUCAST guidelines. Moreover, the in vitroactivity of new antifungal agents against dermatophytes was evaluated. Agreement between the mycelial inoculum method and the CLSI broth microdilution method was high (93% to 100%). Echinocandins (minimal effective concentration [MEC], ≤0.5 mg/liter) and posaconazole (MIC, ≤3.00 mg/liter) showed good activity against all tested dermatophytes. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
