| Autor: |
Al mehy, Gehan F., Abd El-Fattah, Ghada A., Gouda, Mohebat H., El-Sawi, Rasha M., Amer, Mostafa M. |
| Zdroj: |
Egyptian Journal of Chest Diseases and Tuberculosis; July 2015, Vol. 64 Issue: 3 p607-613, 7p |
| Abstrakt: |
Malignant mesothelioma (MM) carries a poor prognosis and response rates to palliative chemotherapy remain low. The diagnosis of malignant mesothelioma is frequently difficult, the most common differential diagnosis being reactive pleural conditions and metastatic adenocarcinoma. Several studies have used immunohistochemical markers to distinguish between reactive and neoplastic mesothelial cells. Soluble mesothelin levels in serum have recently been shown to be highly specific and moderately sensitive for mesothelioma. A combined detection of serum levels of mesothelin and immunohistochemical expression of desmin and EMA are used in order to differentiate between reactive mesothelial proliferations, and malignant mesothelioma of epithelioid type. |
| Databáze: |
Supplemental Index |
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