| Autor: |
Tombropoulos, Elias G., Werbin, Harold, Chaikoff, I. L. |
| Zdroj: |
Experimental Biology and Medicine; June 1962, Vol. 110 Issue: 2 p331-334, 4p |
| Abstrakt: |
The whole homogenate of female rat liver, as well as the centrifugal fraction of mitochondria and microsomes prepared from it, actively converts cholest-4-en-3-one to 5α-cholestan-3β-ol, thereby demonstrating the presence in these fractions of 5α-hydrogenase and 3β-dehydrogenase activities. One or both of these enzymes was absent in the supernatant fraction. A particulate fraction (148,000 X g) prepared from sonically disrupted mitochondria was more active in reducing cholest-4-en-3-one to 5α-cholestan-3β-ol than were the disrupted mitochondria. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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