| Autor: |
Murthy, Lalitha, Petering, Harold G. |
| Zdroj: |
Experimental Biology and Medicine; December 1969, Vol. 132 Issue: 3 p931-935, 5p |
| Abstrakt: |
Rat liver cells prepared by using various dissociating solutions were unable to accumulate K+from the media. The respiration of dissociated liver cells in the presence of succinate was not altered by the presence of 3 × 10-5sodium tetraphenylborate in the dissociating media. Accumulation of K+and respiration in the presence of succinate of rat liver slices were shown to be subject to inhibitory action of TPB on a log-dose basis in the concentration range of 3 × 10-5to 3 × 10-3M.Liver slices exposed to 3 × 10-3MTPB showed the same loss of ability to accumulate K+which was shown by liver cells dissociated by any of the methods tried, whether TPB was present or not. From these studies it is concluded that freshly isolated cells which exhibit oxygen uptake in the presence of succinate are unable to perform other metabolic functions, such as K+uptake. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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