| Autor: |
Turkenkopf, Iris J., Olsen, Janet L., Moray, L., Greenwood, M. R. C., Johnson, P. R. |
| Zdroj: |
Experimental Biology and Medicine; September 1980, Vol. 164 Issue: 4 p530-533, 4p |
| Abstrakt: |
Hepatic lipogenesis was examined during the preweaning and early postweaning period in Zucker fafaand lean rat pups by measuring total in vivolipogenesis and the activity of two rate-limiting lipogenic enzymes, acetyl-CoA carboxylase (ACC) and fatty acid synthetase (FAS). No significant differences in in vivolipogenesis, ACC, and FAS activity were present during the preweaning period. After weaning, total lipogenesis and the two lipogenic enzyme activities, ACC and FAS, were significantly elevated in fafarats compared to lean rats. Thus, early overproduction of lipids by the liver does notappear to be a primary effect of the fagene. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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