Cholesterogenesis During Acute Infection in Chronically Hypercholesterolemic Rhesus Monkeys1

Autor: Fiser, R. H., Denniston, J. C., Kastello, M. D., Rindsig, R. B., Beisel, W. R.
Zdroj: Experimental Biology and Medicine; May 1972, Vol. 140 Issue: 1 p314-318, 5p
Abstrakt: The presence of chronic, experimentally induced hypercholesterolemia in rhesus monkeys led to atypical patterns of lipid response during acute pneumococcal infection. When compared to infection in previously normal monkeys, hypercholesterolemic monkeys showed an impaired synthesis of cholesterol with accumulation of squalene in the plasma, an increased conversion of newly formed cholesterol to an esterified form, and an impaired utilization of triglycerides.
Databáze: Supplemental Index