| Autor: |
Mawhinney, Brian S., Austin, Bruce T., Riley, Edgar F. |
| Zdroj: |
Experimental Biology and Medicine; May 1972, Vol. 140 Issue: 1 p208-211, 4p |
| Abstrakt: |
The results of our experiments indicate that tritiated thymidine, after penetrating the inner shell membrane of the chick egg, is incorporated into those embryonic cells which are synthesizing DNA. The amount of radioactive tracer absorbed is a function of the age of the embryo, the concentration of the isotope dose and the length of the embryos' exposure to the isotope. The uptake of isotope by the embryo may be reproducibly determined and thus the process may be used to determine the effect of various agents on the DNA synthesis of embryonic chick cells. Using this system we are presently studying the effect of ionizing radiation on developing chick embryos.We gratefully acknowledge the constructive criticism and advice of Dr. T. C. Evans. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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