| Autor: |
Burchenal, Joseph H., Waring, Georgia B., Hutchison, Dorris J. |
| Zdroj: |
Experimental Biology and Medicine; October 1951, Vol. 78 Issue: 1 p311-313, 3p |
| Abstrakt: |
(1) By growing Streptococcus jaecalis(ATCC No. 8043) in a medium containing successively higher concentrations of amethopterin, more than a thousand-fold increase in resistance has been achieved. (2) This amethopterin-fast variant has a slightly lower requirement for folic acid in the absence of amethopterin than the parent sensitive strain. In the absence of folic acid, however, amethopterin and certain other 4-amino derivatives of PGA can replace this folic acid requirement in the resistant strain. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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