| Autor: |
Ringler, I., Bortle, L., Heyder, E., Monteforte, A., Perrine, J., Ross, E. |
| Zdroj: |
Experimental Biology and Medicine; December 1959, Vol. 102 Issue: 3 p628-631, 4p |
| Abstrakt: |
Glucocorticoid properties of subcutaneously and orally administered triamcinolone acetonide were assayed in immature adrenalectomized rats by liver glycogen deposition and thymus involution. Subcutaneously, triamcinolone acetonide is about 3 times as potent as triamcinolone on liver glycogen assay and 7 times triamcinolone on the thymolytic assay. Oral activities of triamcinolone acetonide also were greater than those of the parent steroid. Triamcinolone acetonide was capable of inducing a diuretic, natriuretic and kaliuretic response in adrenalectomized rats. Triamcinolone acetonide was more active than either desoxycorticosterone or triamcinolone for maintaining the life of immature, adrenalectomized male rats. |
| Databáze: |
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| Externí odkaz: |
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