| Autor: |
Zanetti, Mary E., Tennent, David M. |
| Zdroj: |
Experimental Biology and Medicine; April 1963, Vol. 112 Issue: 4 p991-995, 5p |
| Abstrakt: |
Pseudopregnant female dogs exhibited a characteristic hypercholesterolemia that was similar to that seen in true pregnancy in this laboratory. Daily subcutaneous injection of progesterone or prolactin raised blood cholesterol concentrations in male, anestrous female, and ovariectomized female dogs. The two hormones differed in their action. Niacin feeding counteracted the hypercholesterolemia of pseudopregnancy, and lowered plasma cholesterol levels in progesterone-injected or prolactin-injected ovariectomized female dogs. It had no effect on cholesterol concentrations of normal male or progesterone-injected male dogs. Niacinamide generally increased plasma cholesterol levels. Sodium benzmalecene lowered the blood cholesterol of a prolactin and a progesterone-injected female, and of a progesterone-injected male dog. Cholestyramine resin decreased the elevated cholesterol level of a progesterone-injected male dog. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
