Autor: |
Matarredona, Jaime, Martín, Roberto, De Salamanca, Rafael Enriquez, Sendagorta, Enrique, Matesanz, Rafael, Perpiña, Julia, Ortuño, Joaquín, Ledo, Antonio |
Zdroj: |
The Journal of Dermatology; October 1985, Vol. 12 Issue: 5 p410-415, 6p |
Abstrakt: |
Bullous dermatosis developed in three patients with renal failure who were on maintenance hemodialysis. On clinical and histological grounds, skin lesions were indistinguishable from those of porphyria cutanea tarda. A highly sensitive fluorimetric thin‐layer chromatographic technique was used for assay of porphyrin levels in plasma, urine, feces and dialysate. The porphyrin metabolism alterations observed in our three patients were not sufficiently uniform to be considered the cause of the bullous dermatosis. Uroporphyrinogen decarboxylase activities in red cells were also within normal limits. No other common etiological factors could be identified in our patients. |
Databáze: |
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