PAR-2 Deficient CD4+T Cells Exhibit Downregulation of IL-4 and Upregulation of IFN-γ after Antigen Challenge in Mice

Autor: Shichijo, Michitaka, Kondo, Shinichi, Ishimori, Mina, Watanabe, Shinichi, Helin, Heidi, Yamasaki, Tsugiko, Stevens, Mary E, Gantner, Florian, Bacon, Kevin B
Zdroj: Allergology International; January 2006, Vol. 55 Issue: 3 p271-278, 8p
Abstrakt: To investigate the functional role of protease activated receptor (PAR) -2 in T lymphocytes, we analyzed TCR-mediated inflammatory cytokine production using PAR-2 deficient (KO) and wild type (WT) mice.
Databáze: Supplemental Index