Release of a Synaptically Active Material by Nicotine in the Central Nervous System of the American Cockroach

Autor: Flattum, Roger F., Sternburg, James G.
Zdroj: Journal of Economic Entomology; February 1970, Vol. 63 Issue: 1 p67-67, 1p
Abstrakt: Nicotine causes the release of a synaptically active material from the abdominal nerve cord of Periplaneta americalla (L.). Reapplication of a nicotine bathing solution to nicotine-recovered American cockroach preparation results in a 2nd block. The synaptically active material in bathing solutions is unstable and is lost if left at room temperature (24°C) 1 hour, or made alkaline. It is stable in an acidic environment. It is dialyzable and ethanol soluble. Two components of this material have been chromatographically separated, one which depresses and blocks and another which excites and blocks spontaneous activity and synaptic propagation.
Databáze: Supplemental Index