| Autor: |
Sardari, Soroush, Mori, Yoki, Horita, Kiyoshi, Micetich, Ronald G, Nishibe, Sansei, Daneshtalab, Mohsen |
| Zdroj: |
Bioorganic & Medicinal Chemistry; September 1999, Vol. 7 Issue: 9 p1933-1940, 8p |
| Abstrakt: |
Angelicin, a naturally occurring furanocoumarin, that showed antifungal activity, was considered as a lead structure for a group of synthetic coumarins. Antifungal activities of the synthesized coumarins and angelicin derivatives were reported against Candida albicans, Cryptococcus neoformans, Saccharomyces cerevisiaeand Aspergillus niger. Human cell line cytotoxicity of several coumarins was evaluated against KB cells. Angelicin and several potent antifungals showed to be non-toxic in this assay. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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