| Autor: |
Jansen, Ruud, Briaire, Jan, Kamp, Elbarte M., Gielkens, Arno L.J., Smits, Mari A. |
| Zdroj: |
FEMS Microbiology Letters; February 1995, Vol. 126 Issue: 2 p139-139, 1p |
| Abstrakt: |
Actinobacillus pleuropneumoniae shows synergistic haemolysis when cocultured with Staphylococcus aureus on blood agar plates. This CAMP effect has been attributed to a discrete CAMP factor, but also to the A. pleuropneumoniae-RTX-toxins I, II, and III. We examined the CAMP effect of recombinant Escherichia coli strains that secreted each of these toxins, and of A. pleuropneumoniae mutant strains that were devoid of one or more these toxins. We found that the E. coli strains were CAMP positive, whereas the A. pleuropneumoniae strain devoid of functional toxin genes was CAMP negative. This demonstrated that the CAMP effect of A. pleuropneumoniae is caused by the toxins and that no CAMP factor per se exists. |
| Databáze: |
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