| Autor: |
John Murray, P., Harrison, Lee A., Johnson, Martin R., Robertson, Graeme M., Scopes, David I.C., Bull, David R., Graham, Elizabeth A., Hayes, Ann G., Kilpatrick, Gavin J., Daas, Izaak Den, Large, Charles, Sheehan, Michael J., Stubbs, Carole M., Turpin, Michael P. |
| Zdroj: |
Bioorganic & Medicinal Chemistry Letters; 1995, Vol. 5 Issue: 3 p219-222, 4p |
| Abstrakt: |
A novel series of arylpiperazines has been synthesised which show high affinity for dopamine D3 receptors. Several of these compounds exhibit ca. 100 fold selectivity for the dopamine D3 receptor over D1, D2 and D4 receptors. In vivo studies suggest that 4 (GR103691) may have an atypical antipsychotic profile. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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