| Autor: |
Mendes do Nascimento, Andréa, Costa, Fernanda Cristina, Thiemann, Otavio Henrique, Rodrigues de Oliveira, Dionéia Camilo |
| Zdroj: |
Zeitschrift für Naturforschung C; June 2007, Vol. 62 Issue: 5-6 p353-356, 4p |
| Abstrakt: |
The dichloromethane extract of Calea uniflora afforded a mixture of two novel chromanones, uniflorol-A (1) and uniflorol-B (2), and one known chromanone, 2,2-dimethyl-6- (1-hydroxyethyl)-chroman-4-one (3). The structures of these compounds were determined by spectroscopic methods. Biological activity of the compounds against Leishmania major promastigotes was evaluated. Mixture of the novel chromanones 1 and 2 showed significant growth inhibition of the parasite in the micrograms per milliliter range. |
| Databáze: |
Supplemental Index |
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