Stimulation of Pancreatic Lipase Activity by Saponins Isolated from Medicago sativa L.

Autor: Sroka, Zbigniew, Jurzysta, Marian, Tylcz, Joanna, Rzadkowska-Bodalska, Halina
Zdroj: Zeitschrift für Naturforschung C; April 1997, Vol. 52 Issue: 3-4 p235-239, 5p
Abstrakt: Saponins isolated from Medicago sativa L. appeared to stimulate lipolytic activity and did not influence amylolytic or proteolytic activity of Neopancreatinum (extract of pancreatic enzymes: lipase, proteases and amylases). Saponins isolated from the aerial part of Medicago sativa L. were demonstrated to stimulate lipase activity more effectively than saponins sepa­ rated from the root of this plant. When saponins were treated with 0.02 m HC1 at 37 °C for 1 hour their lipase stimulation ability did not change. The saponins stimulated Neopancreatinum lipolytic activity more in­ tensively in the presence of sodium cholate.
Databáze: Supplemental Index