Isolation of Two Cytotoxic Diterpenes from the Fern Pteris multifida

Autor: Woerdenbag, Herman J., Lutke, Bos, Rein, Stevens, Jan F., Hulst, Ron, Kruizinga, Wim H., Zhu, You-Ping, Elema, Elizabeth T., Hendriks, Henk, Uden, Wim van, Pras, Niesko
Zdroj: Zeitschrift für Naturforschung C; October 1996, Vol. 51 p635-638, 4p
Abstrakt: From aerial parts of the fern Pteris multifida Poir. (Polypodiaceae) two diterpenes, entkaurane- 2ß,16a-diol and ent-kaur-16-ene-2ß,15a-diol, were isolated by repeated column chromatography using silica gel and silica gel impregnated with silver nitrate. The structures were confirmed by spectroscopic methods. Both compounds showed a moderate cytotoxicity to Ehrlich ascites tumour cells
Databáze: Supplemental Index