Autor: |
Toshkova, Reneta A., Dimitrova, Petia A., Ivanova, Emilia H., Dolashka, Pavlina A., Angelova, Maria B., Pashova, Svetlana B., Slokoska, Ludmila S., Voelter, Wolfgang |
Zdroj: |
Zeitschrift für Naturforschung C; August 2000, Vol. 55 Issue: 7-8 p649-656, 8p |
Abstrakt: |
Investigation on the immunoprotective activity of Cu/Zn superoxide dismutase from Humicola lutea 103 AL (HLSOD) in hamsters with transplanted myeloid tumor was performed. Survivability, tumor growth and tumor transplantability were followed. The immune status of tumor-bearing animals, injected with the optimal protective HLSOD dose, was examined during 27 days after tumor transplantation by the following parameters: (i) the number, migration and phagocytic activity of peritoneal macrophages, (ii) the phagocytic activity of blood polymorphonuclear leukocytes (PMNs), (iii) the responsibility in vitro of spleen lymphocytes to T and B cell mitogens. |
Databáze: |
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