| Autor: |
Leising, H. B., Schachtschabel, D.O. |
| Zdroj: |
Zeitschrift für Naturforschung C; February 1979, Vol. 34 Issue: 1-2 p124-130, 7p |
| Abstrakt: |
Purified melanosomes isolated from subcutaneously growing Harding-Passey melanomas of NMRI-mice were labeled either in vitro with [14C] tyrosine or [14C]DOPA in the melanin portion, or in vivo in the melanin and protein portion following i. p. injection of [14C] tyrosine. Treatment of monolayer cultures of Harding-Passey melanoma cells (HPM-73 line) with such labeled melanosomes resulted in rapid uptake of label during the first 4 h which leveled off thereafter. A portion of the “incorporated” label could be removed by a 15 min chase with unlabeled melanosomes. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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