| Autor: |
Yeo, Jeremy C., Wall, Adam A., Luo, Lin, Stow, Jennifer L. |
| Zdroj: |
Molecular Biology of the Cell; March 2015, Vol. 26 Issue: 5 p952-965, 14p |
| Abstrakt: |
Rab31 recruits APPL2 to regulate phagocytic cup closure and FcγR signaling pathways via production of PI(3,4,5)P3in macrophages. APPL2 is poised to activate macrophages and act as a counterpoint to APPL1 in FcγR-mediated PI3K/Akt signaling. New locations and roles are found for Rab31 and APPL2 by which they contribute to innate immune functions. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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