Genetic Predisposition to Purine Uroliths in Dalmatian Dogs

Autor: Schaible, Robert H.
Zdroj: Veterinary Clinics of North America: Small Animal Practice; January 1986, Vol. 16 Issue: 1 p127-131, 5p
Abstrakt: Homozygosity for a defective recessive gene results in all Dalmatians having elevated concentrationS of urine uric acid and predisposes them to formation of purine uroliths. Urine uric acid values for Dalmatians reported in the literature are not likely to be comparable, because uric acid appears to be more likely to precipitate in Dalmatian urine than in the urine of other dogs and man. Heating, alkalinization, and thorough mixing are required whenever specimens are transferred from one container to another or an aliquot is removed for assay.
Databáze: Supplemental Index