| Autor: |
Simmons, Michael J., Peterson, Mark P., Thorp, Michael W., Buschette, Jared T., DiPrima, Stephanie N., Harter, Christine L., Skolnick, Matthew J. |
| Zdroj: |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis; March 2015, Vol. 773 Issue: 1 p16-21, 6p |
| Abstrakt: |
•We screened for new X-linked lethal mutations in the germ lines of male flies.•The flies carried mutant alleles of genes involved in transposon regulation.•Mutant ago3alleles did not affect the germ-line mutation rate.•Mutant piwiand Su(var)205(HP1) alleles tripled the germ-line mutation rate.•Depletion of chromatin-organizing proteins Piwi or HP1 may de-repress transposons. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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