Autor: |
Sze, S H, Roytberg, M A, Gelfand, M S, Mironov, A A, Astakhova, T V, Pevzner, P A |
Zdroj: |
Bioinformatics; 1998, Vol. 14 Issue: 1 p14-19, 6p |
Abstrakt: |
Gene annotation is the final goal of gene prediction algorithms. However, these algorithms frequently make mistakes and therefore the use of gene predictions for sequence annotation is hardly possible. As a result, biologists are forced to conduct time-consuming gene identification experiments by designing appropriate PCR primers to test cDNA libraries or applying RT-PCR, exon trapping/amplification, or other techniques. This process frequently amounts to 'guessing' PCR primers on top of unreliable gene predictions and frequently leads to wasting of experimental efforts. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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