| Autor: |
Heber, Steffen, Alekseyev, Max, Sze, Sing-Hoi, Tang, Haixu, Pevzner, Pavel A |
| Zdroj: |
Bioinformatics; 2002, Vol. 18 Issue: Supplement 1 pS181-S188, 8p |
| Abstrakt: |
The traditional approach to annotate alternative splicing is to investigate every splicing variant of the gene in a case-by-case fashion. This approach, while useful, has some serious shortcomings. Recent studies indicate that alternative splicing is more frequent than previously thought and some genes may produce tens of thousands of different transcripts. A list of alternatively spliced variants for such genes would be difficult to build and hard to analyse. Moreover, such a list does not show the relationships between different transcripts and does not show the overall structure of all transcripts. A better approach would be to represent all splicing variants for a given gene in a way that captures the relationships between different splicing variants. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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