Complete Nucleotide Sequences of Two NDM-1-Encoding Plasmids from the Same Sequence Type 11 Klebsiella pneumoniaeStrain

Autor: Studentova, V., Dobiasova, H., Hedlova, D., Dolejska, M., Papagiannitsis, C. C., Hrabak, J.
Zdroj: Antimicrobial Agents and Chemotherapy; November 2014, Vol. 59 Issue: 2 p1325-1328, 4p
Abstrakt: ABSTRACTThe sequence type 11 Klebsiella pneumoniaestrain Kpn-3002cz was confirmed to harbor two NDM-1-encoding plasmids, pB-3002cz and pS-3002cz. pB-3002cz (97,649 bp) displayed extensive sequence similarity with the blaNDM-1-carrying plasmid pKPX-1. pS-3002cz (73,581 bp) was found to consist of an IncR-related sequence (13,535 bp) and a mosaic region (60,046 bp). A 40,233-bp sequence of pS-3002cz was identical to the mosaic region of pB-3002cz, indicating the en blocacquisition of the NDM-1-encoding region from one plasmid by the other.
Databáze: Supplemental Index