Molecular Characterization of blaNDM-5Carried on an IncFII Plasmid in an Escherichia coliIsolate from a Nontraveler Patient in Spain

Autor: Pitart, Cristina, Solé, Mar, Roca, Ignasi, Román, Angely, Moreno, Asunción, Vila, Jordi, Marco, Francesc
Zdroj: Antimicrobial Agents and Chemotherapy; October 2014, Vol. 59 Issue: 1 p659-662, 4p
Abstrakt: ABSTRACTA carbapenem-resistant Escherichia coliisolate (sequence type 448 [ST448]) was recovered from a urine culture of a female patient with no recent record of traveling. PCR screening identified the presence of blaNDM-5, blaTEM-1, blaOXA-1, blaCMY-42, and rmtB. blaNDM-5was carried in a conjugative IncFII-type plasmid (90 kb) together with blaTEM-1and rmtB. The genetic environment of blaNDM-5showed a structure similar to those of pMC-NDM and pGUE-NDM, identified in Poland and France in E. coliof African and Indian origin, respectively.
Databáze: Supplemental Index