| Autor: |
Boymans, Evert H., Witte, P. T., Vogt, D. |
| Zdroj: |
Catalysis Science & Technology; 2014, Vol. 5 Issue: 1 p176-183, 8p |
| Abstrakt: |
A supported Pt nanoparticle-based catalyst was used in the chemoselective hydrogenation of nitroarenes to N-arylhydroxylamines (N-AHA). Optimization of NB hydrogenation conditions showed that substantially higher N-PHA yields can be obtained at low temperature. Especially, the influence of an increased hydrogen pressure on selectivity is remarkable. Maximum yields increase from 55% N-PHA at 4 bar H2to 80% at 23 bar H2in ethanol. Further optimization led to the use of small amounts of amine additive, TMEDA, with 50 bar H2raising the maximum yield to 97% N-PHA. The decreased N-PHA hydrogenation rate at high H2pressure and the presence of TMEDA allow for selective transformation of a range of other nitroarenes containing electron-withdrawing and -donating (reducible) functional groups to their N-AHAs in excellent (more than 90%) yields. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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