| Autor: |
Horimoto, Alex Magno Coelho, da Costa, Izaias Pereira |
| Zdroj: |
Revista Brasileira de Reumatologia (English Edition); 20240101, Issue: Preprints |
| Abstrakt: |
Systemic sclerosis (SSc) is a connective tissue disease of autoimmune nature characterized by the triad of vascular injury, autoimmunity (cellular and humoral) and tissue fibrosis. Autoantibodies do not seem to be simply epiphenomena, but are involved in disease pathogenesis. It is believed that the SSc-specific autoantibodies are responsible both for amplifying immune response and targeting cell types that are relevant in the pathophysiology of SSc. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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