Acute heart failure after venlafaxine overdose: Post-mortem myocardial examination in two cases

Autor: Hantson, Philippe, Batista, Mélissa, Fonseca, Sandhya, Ferreira, Ingrid, Haufroid, Vincent, Capron, Arnaud, Bonbled, Frédéric, Cosyns, Jean-Pierre
Zdroj: Toxicologie Analytique et Clinique; December 2014, Vol. 26 Issue: 4 p193-196, 4p
Abstrakt: Large overdoses of venlafaxine may induce acute heart failure with severe left ventricular dysfunction. We describe two fatal cases of venlafaxine poisoning documented by post-mortem myocardial ultrastructural examination and by the determination of venlafaxine (VEN) and O-desmethylvenlafaxine (ODV) concentrations in cardiac tissue.
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