Hyperlipidemia and Hypothyroidism Among Metastatic Renal Cell Carcinoma Patients Taking Sunitinib Malate. Related or Unrelated Adverse Events?

Autor: Tassi, Renato, Baldazzi, Valentina, Lapini, Alberto, Carini, Marco, Mazzanti, Roberto
Zdroj: Clinical Genitourinary Cancer; 20240101, Issue: Preprints
Abstrakt: Thyroid function impairment is commonly observed in patients with metastatic renal cell carcinoma receiving sunitinib. Effects of sunitinib on serum lipids are not described but could depend on a hypothyroid state. We evaluated serum lipids in 39 consecutive patients taking sunitinib. A hyperlipidemic state was observed and was related to drug toxicity. Careful monitoring of serum lipids during sunitinib administration is recommended.
Databáze: Supplemental Index