A Multicenter Study of PneumocystisChoroidopathy

Autor: Shami, Michel J., Freeman, William, Friedberg, Dorothy, Siderides, Elizabeth, Listhaus, Allen, Ai, Everett
Zdroj: American Journal of Ophthalmology; July 1991, Vol. 112 Issue: 1 p15-22, 8p
Abstrakt: We studied 21 patients with the acquired immunodeficiency syndrome and presumed Pneumocystis cariniichoroidopathy. The lesions were characteristically yellow to pale yellow in color, appeared at the level of the choroid, and were found in the posterior pole. They varied in size from 300 to 3,000 um, initially increasing in number before treatment and eventually resolving after systemic antimicrobial therapy. Of the 21 patients, 18 (86%) had received inhaled pentamidine as prophylaxis against Pneumocystispneumonia. Visual acuity and visual field testing showed little evidence of retinal destruction. Survival after the diagnosis of the choroidopathy ranged from two to 36 weeks. Pneumacystischoroidopathy offers an easily accessible due to disseminated Pneumocystisinfection. When comparing drugs for Pneumacystisprophylaxis, careful ocular examination can provide one indicator of the relative efficacy of protection against extrapulmonary disease.
Databáze: Supplemental Index