| Autor: |
Patel, Achyut S., Hemady, Ramzi K., Rodrigues, Merlyn, Rajagopalan, Sankaran, Elman, Michael J. |
| Zdroj: |
American Journal of Ophthalmology; March 1994, Vol. 117 Issue: 3 p363-368, 6p |
| Abstrakt: |
Endogenous fungal endophthalmitis is an uncommon complication of systemic mycosis. Only a few cases involving Fusariumhave been reported, most with unfavorable visual outcomes. We examined a 31-year-old woman with acute lymphocytic leukemia who developed sudden visual loss in her right eye. A dense, white placoid infiltrate was present in the right macula extending into the vitreous. An iris nodule and hypopyon were present in the left eye. A vitreous aspirate of the right eye was positive for Fusariumspecies. The patient progressively lost vision despite amphotericin B and 5-fluorocytosine therapy. She died from bronchopneumonia, fungemia, and multisystem failure. Histopathologic study disclosed a panophthalmitis with Fusariumorganisms invading all the ocular coats in the right eye. Leukemic infiltrates were present in the left iris, anterior chamber, and trabecular meshwork. The ocular destructiveness of Fusariummay be caused by marked mycotic vascular invasion and occlusion with consequent infarction and necrosis of ocular tissues. |
| Databáze: |
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