| Autor: |
Matsuda, Mamoru, MacRae, Scott M., Inaba, Masamaru, Manabe, Reizo |
| Zdroj: |
American Journal of Ophthalmology; March 1989, Vol. 107 Issue: 3 p246-251, 6p |
| Abstrakt: |
Using wide-field specular microscopy, we evaluated the morphologic features of the corneal endothelium in 14 eyes of 14 patients with keratoconus who had worn a polymethylmethacrylate hard contact lens for at least four years (mean, 71 months) after penetrating keratoplasty. Comparisons were made with 14 non-lens-wearing eyes of 14 patients with keratoconus matched for age, length of postoperative period, and other variables. Examination of the endothelium of the contact lens wearers showed a significantly higher coefficient of variation in cell size (polymegethism) and a marked decrease in the percentage of hexagonal cells (pleomorphism), with a significant decrease in cell density (P < .05). The cause of these morphologic abnormalities remains unclear but may be related to lens-induced hypoxic stress to the corneal endothelium causing ongoing cell loss. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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