| Autor: |
Camras, Carl B., Feldman, Sanford G., Podos, Steven M., Christensen, Robert E., Gardner, Susanne K., Fazio, Doreen T. |
| Zdroj: |
American Journal of Ophthalmology; July 1985, Vol. 100 Issue: 1 p169-175, 7p |
| Abstrakt: |
In a prospective, randomized, double-masked study, 2% epinephrine applied topically twice each day for two weeks to the eyes of patients with glaucoma or ocular hypertension caused an 8.1 ± 1.4–mm Hg (mean ± S.E.M.) reduction of intraocular pressure in placebo-treated patients, but only a 1.9 ± 0.6–mm Hg decrease in patients treated with 25 mg of orally administered indomethacin four times each day (P <.0005). Systemic treatment with indomethacin for one week did not significantly increase intraocular pressure by itself (baseline, 19.7 ± 0.6 mm Hg, vs 20.1 ± 1.4 mm Hg after indomethacin treatment). When indomethacin treatment was discontinued in those patients receiving topical epinephrine, there was a further significant (P <.05) reduction in intraocular pressure compared with the placebo-treated group. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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