| Autor: |
Moreira, Raquel R.D., Martins, Gilmarcio Z., Pietro, Rosemeire C.L.R., Sato, Daisy N., Pavan, Fernando R., Leite, Sergio R.A., Vilegas, Wagner, Leite, Clarice Q.F. |
| Zdroj: |
Revista Brasileira de Farmacognosia; March-April 2013, Vol. 23 Issue: 2 p268-272, 5p |
| Abstrakt: |
Paepalanthusspp., Eriocaulaceae, are native plants from Brazil known as “sempre-vivas” (everlasting flowers). In this work, we evaluated the potential anti-mycobacterial activity of two methoxylated flavonoids (flavonoid 7-methylquercetagetin and 7-methylquercetagetin-4′-O-β-D-glucopyranoside) isolated and identified from P. latipesand the naphthopyranone fractions from P. bromeliodesethanolic extracts. The MIC value of 500μg/mL was verified for all compounds tested against M. tuberculosisH37Rv. For M. avium, the MIC value ranged from 1000–2000μg/mL excepting to naphthopyranone fractions with MIC of 500μg/mL. This is the first report of activity determination of Paepalanthusspp. flavonoids activity against Mycobacterium tuberculosisand M. avium. |
| Databáze: |
Supplemental Index |
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