| Autor: |
WEIDNER, Stefan, GOEKE, Klaus, TRINKS, Uwe, TRAXLER, Peter, UCCI-STOLL, Katharina, GHISALBA, Oreste |
| Zdroj: |
Bioscience, Biotechnology, and Biochemistry; January 1999, Vol. 63 Issue: 8 p1497-1500, 4p |
| Abstrakt: |
A microbial screening indicated that two fungal strains, Beauveria bassianaDSM 1344=ATCC 7159 and Cunninghamella elegansDSM 1908=ATCC 9245, as well as four bacterial strains belonging to the genus Streptomyceswere able to hydroxylate 4,5-dianilinophthalimide (DAPH, CGP52411) to 4-(4′-hydroxyanilino)-5-anilinophthalimide. Cunninghamella elegansDSM 1908 turned out to be the most active biocatalyst and was also able to form the dihydroxy derivative, 4,5-bis(4′-hydroxyanilino)phthalimide. The reaction for the monohydroxylated biotransformation product was carried out on a preparative scale, and the culture conditions for the formation of 4-(4′-hydroxy- anilino)-5-anilinophthalimide with this strain were op-timized. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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