| Autor: |
HUNG, Pham, KAKU, Shihoko, YUNOKI, Shin-ichi, OHKURA, Ken-ichi, GU, Jiong-Yan, IKEDA, Ikuo, SUGANO, Michihiro, YAZAWA, Kazunaga, YAMADA, Koji |
| Zdroj: |
Bioscience, Biotechnology, and Biochemistry; January 1999, Vol. 63 Issue: 1 p135-140, 6p |
| Abstrakt: |
The dietary effect of fish oils (FOs) rich in eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) on the immune function of Sprague-Dawley rats was compared with that of safflower oil. After 3 weeks of feeding at the 10% level of a dietary fat, the IgG and IgM production by splenocytes and IgG production by mesenteric lymph node (MLN) lymphocytes were significantly higher in the FO-fed rats, while no significant difference was found in IgA or IgE productivity by both the spleen and MLN lymphocytes. In the FO-fed rats, peritoneal exudate cells released a lower amount of LTB4, reflecting their lower arachidonic acid level, and a higher amount of LTB5, reflecting their higher EPA level in phospholipids. On these EPA-rich FO exerted a stronger effect than DHA-rich FO immune functions. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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