Plasma beta-endorphin and beta-lipotropin levels increase in well trained athletes after competition and non competitive exercise

Autor: Petraglia, Felice, Modena, A., Comitini, G., Scazzina, D., Facchinetti, F., Fiaschetti, D., Genazzani, A., Barletta, C., Scavo, D., Genazzani, A.
Zdroj: Journal of Endocrinological Investigation; January 1990, Vol. 13 Issue: 1 p19-23, 5p
Abstrakt: Plasma ß-endorphin (ß-EP) and ß-lipotropin (ß-LPH) levels were measured in 15 healthy trained marathon runners. These hormones were evaluated in two different conditions: 1 — before (1 h) and after a marathon race (n = 10); 2 — before, during and after a prolonged (90 min) submaximal exercise (bicycle ergometer at 50% VO2max) (n = 5). In these latter group plasma ß-EP and ß-LPH levels were measured every 15 min for 165 min. In all the athletes, both plasma ß-EP and ß-LPH levels were significantly higher after the end of the marathon race than in basal conditions (p < 0.01). The prolonged exercise with bicycle ergometer significantly stimulated plasma ß-EP and ß-LPH levels. Starting 60 min after the beginning of the exercise, plasma ß-EP and ß-LPH levels resulted significantly higher than basal values until the end of the exercise (p < 0.01 at 60, 75 and 90 min). These data confirming that marathon running is a potent stress stimulus, showed that the duration and related factors but not the work load may be considered critical in stimulating ß-EP and ß-LPH release during physical exercise.
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