Epigenetic Reprogramming of HOXC10in Endocrine-Resistant Breast Cancer

Autor: Pathiraja, Thushangi N., Nayak, Shweta R., Xi, Yuanxin, Jiang, Shiming, Garee, Jason P., Edwards, Dean P., Lee, Adrian V., Chen, Jian, Shea, Martin J., Santen, Richard J., Gannon, Frank, Kangaspeska, Sara, Jelinek, Jaroslav, Issa, Jean-Pierre J., Richer, Jennifer K., Elias, Anthony, McIlroy, Marie, Young, Leonie S., Davidson, Nancy E., Schiff, Rachel, Li, Wei, Oesterreich, Steffi
Zdroj: Science Translational Medicine; March 2014, Vol. 6 Issue: 229 p229ra41-229ra41, 1p
Abstrakt: Genome-wide screen identifies methylation of the estrogen-repressed HOXC10gene as a determinant of resistance to aromatase inhibitors in breast cancer.
Databáze: Supplemental Index