Naltrexone has no effects on body weights of starving rats

Autor: Reid, Larry, Wideman, Janusz
Zdroj: Bulletin of the Psychonomic Society; May 1982, Vol. 19 Issue: 5 p298-300, 3p
Abstrakt: Thirty rats (10 rats/group) were fixed with devices for the chronic delivery of naltrexone (1.2 or 2.4 mg/rat/day) or saline. Then, they were subjected to deprivation of food and water for 4 days, during which their body weights were measured twice daily. The rats with naltrexone lost body weight at rates very similar to those of rats receiving saline. This observation is at variance with recent formulations concerning the ordinary functions of the endorphins. Naltrexone suppressed water and food intakes when food and water were presented after the 96-h starvation period.
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