Functionalized main-group organometallics for organic synthesis

Autor: Knochel, Paul, Hupe, Eike, Dohle, Wolfgang, Lindsay, David M., Bonnet, Véronique, Quéguiner, Guy, Boudier, Andreas, Kopp, Felix, Demay, Stéphane, Seidel, Naka, Calaza, M. Isabel, Vu, Viet Anh, Sapountzis, Ioannis, Bunlaksananusorn, Tanasri
Zdroj: Pure & Applied Chemistry; January 2002, Vol. 74 Issue: 1 p11-17, 7p
Abstrakt: Highly functionalized Grignard-reagents can be easily obtained by an iodine­magnesim exchange reaction and further reacted with various electrophiles. Via a B­Zn exchange reaction, a formal Michael addition with umpolung of the reactivity can be achieved. Chiral phosphine ligands can be easily synthesized by a 2.3 sigmatropic rearrangement and used successfully in asymmetric synthesis.
Databáze: Supplemental Index