Autor:	Hurst, R. O., Kuksis, A.
Zdroj:	Canadian Journal of Physiology and Pharmacology; September 1958, Vol. 36 Issue: 9 p919-929, 11p
Abstrakt:	An extensive destruction of deoxyribonucleic acid has been observed during prolonged treatment with 1 Nsodium hydroxide at 100° C. After 4 hours of hot alkaline hydrolysis there was complete destruction of cytosine, only about 50% of which could be accounted for by conversion to uracil; adenine was destroyed to the extent of 60% without deamination to hypoxanthine, whereas guanine and thymine were not affected. The diphenylamine color test for deoxyribose showed a decrease of 35% and a similar decrease was obtained with the cysteine – sulphuric acid test. A decrease of 26% in the ultraviolet light absorption corresponded to the value calculated on the basis of the destruction of the purine and pyrimidine bases.
Databáze:	Supplemental Index
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