| Autor: |
Kater, Louis, Gmelig-Meyling, Frits H. J., Derksen, Ron H. W. M., de la Faille, Harold Baart |
| Zdroj: |
BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals, and Gene Therapy; December 1995, Vol. 4 Issue: 6 p471-493, 23p |
| Abstrakt: |
The aetiopathogenesis of systemic lupus erythematosus (SLE) is thought to comprise the combined action of hormonal influences and other factors, partly of exogenous and partly of endogenous nature, which leads to the production of autoantibodies and/or lymphoid cells, resulting in inflammatory processes. The fundamental characteristic is the occurrence in blood of autoantibodies against intranuclear cell components, usually designated as antinuclear antibodies. In addition, autoantibodies against cytoplasmically located antigens occur. |
| Databáze: |
Supplemental Index |
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