Recent Developments in the Synthesis of Annonaceous Acetogenins

Autor: Marshall, James A., Hinkle, Kevin W., Hagedorn, Chad E.
Zdroj: Israel Journal of Chemistry; 1997, Vol. 37 Issue: 1 p97-107, 11p
Abstrakt: Synthetic routes to various bis‐THF annonaceous acetogenins and prototypes thereof are reviewed. These C35–C37long‐chain diethers exhibit a remarkable range of biological activities. The core unit, with six oxygenated stereogenic centers, provides a challenging target for asymmetric synthesis.
Databáze: Supplemental Index