Interleukin-1β induces long-term increase of axonally transported opiate receptors and substance P

Autor: Jeanjean, A.P., Moussaoui, S.M., Maloteaux, J.-M., Laduron, P.M.
Zdroj: Neuroscience; 1995, Vol. 68 Issue: 1 p151-157, 7p
Abstrakt: Interleukin-1 is known to exert pleiotropic effects in host defence mechanisms and in inflammation. Chronic pain, inflammation and interleukin-1β enhance the production of substance P. Recently, axonal transport of opiate receptors was found to increase in rat sciatic nerves in the model of Freund's adjuvant-induced arthritis.
Databáze: Supplemental Index