| Autor: |
KENDRA, J., BARRETT, A.J., LUCAS, C., JOSHI, R., JOSS, V., DESAI, M., HALIL, O., ROGERS, T.R., HOBBS, J.R., HUGH‐JONES, K. |
| Zdroj: |
Clinical & Laboratory Haematology; March 1981, Vol. 3 Issue: 1 p19-26, 8p |
| Abstrakt: |
SummaryHigh dose methyl prednisolone (HDMP) was used to treat 25 episodes of graft versus host disease (GVHD) in 13 patients after bone marrow transplantation for aplastic anaemia or acute leukaemia. All patients showed rapid improvement of GVHD following HDMP with resolution of gut and skin manifestations over several days, but liver GVHD was less responsive to treatment. The major complication of treatment was infection and four patients died from infection following HDMP. The mode of action of HDMP may be a nonspecific anti‐inflammatory effect but it appears to be rapidly effective in controlling GVH reactions. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
Plný text