Globally Expanding Carbapenemase Finally Appears in Spain: Nosocomial Outbreak of Acinetobacter baumanniiProducing Plasmid-Encoded OXA-23 in Barcelona, Spain

Autor: Mosqueda, Noraida, Espinal, Paula, Cosgaya, Clara, Viota, Sergio, Plasensia, Virginia, Álvarez-Lerma, Francisco, Montero, Milagro, Gómez, Julià, Horcajada, Juan Pablo, Vila, Jordi, Roca, Ignasi
Zdroj: Antimicrobial Agents and Chemotherapy; July 2013, Vol. 57 Issue: 10 p5155-5157, 3p
Abstrakt: ABSTRACTResistance of Acinetobacter baumanniiclinical isolates to carbapenems is on the rise worldwide mainly in association with the production of OXA-23. Until recently, however, OXA-23 was absent in Spain. In this work, we report the molecular characterization of a hospital outbreak of OXA-23-producing A. baumanniiin Barcelona caused by a multidrug-resistant (MDR) clone belonging to international clone IC-II/sequence type ST85 between October 2010 and May 2011. blaOXA-23was carried in a plasmid of 90 kb and located within the composite transposon Tn2006.
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