| Autor: |
Shibahara, Mariko, Nanko, Hiroko, Shimizu, Mina, Kanda, Naoko, Kubo, Masahide, Ikeda, Michiko, Matsumoto, Masao, Nonaka, Shuko, Shimizu, Hiroshi |
| Zdroj: |
Dermatology; January 2002, Vol. 204 Issue: 1 p37-42, 6p |
| Abstrakt: |
Background:Although dermatitis herpetiformis (DH) is a relatively common disease in Caucasian populations, it is rare in Asian populations including the Japanese. We encountered a Japanese case of DH which showed granular IgA and C3 deposits in the papillary dermis and which was associated with gluten-sensitive enteropathy but no HLA-B8/DR3/DQ2. Objective:The purpose of this study is to describe the characteristics of Japanese DH cases, since most of them have been reported in Japanese language and dermatologists outside Japan are not familiar with the characteristics of Japanese DH. Methods:We have reviewed all 34 Japanese DH cases reported previously. Results:We found several features of Japanese DH compared with Caucasian DH, such as a high frequency of the fibrillar pattern, rarity of gluten-sensitive enteropathy and an absence of the HLA-B8/DR3/DQ2 haplotype. Conclusion:There might be significant differences in pathophysiology between Caucasian and Japanese DH cases. |
| Databáze: |
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